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In vivo imaging xenograft models for the evaluation of anti‐brain tumor efficacy of targeted drugs

Molecular‐targeted drugs are generally effective against tumors containing driver oncogenes, such as EGFR,ALK, and NTRK1. However, patients harboring these oncogenes frequently experience a progression of brain metastases during treatment. Here, we present an in vivo imaging model for brain tumors u...

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Detalles Bibliográficos
Autores principales: Kita, Kenji, Arai, Sachiko, Nishiyama, Akihiro, Taniguchi, Hirokazu, Fukuda, Koji, Wang, Rong, Yamada, Tadaaki, Takeuchi, Shinji, Tange, Shoichiro, Tajima, Atsushi, Nakada, Mitsutoshi, Yasumoto, Kazuo, Motoo, Yoshiharu, Murakami, Takashi, Yano, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727243/
https://www.ncbi.nlm.nih.gov/pubmed/29125233
http://dx.doi.org/10.1002/cam4.1255