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Glucagon‐like peptide‐1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP‐1 receptors

Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone increasing postprandial insulin release. GLP‐1 also induces diuresis and natriuresis in humans and rodents. The GLP‐1 receptor is extensively expressed in the renal vascular tree in normotensive rats where acute GLP‐1 treatment leads to increase...

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Detalles Bibliográficos
Autores principales: Ronn, Jonas, Jensen, Elisa P., Wewer Albrechtsen, Nicolai J., Holst, Jens Juul, Sorensen, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727271/
https://www.ncbi.nlm.nih.gov/pubmed/29233907
http://dx.doi.org/10.14814/phy2.13503