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Gestation changes sodium pump isoform expression, leading to changes in ouabain sensitivity, contractility, and intracellular calcium in rat uterus

Developmental and tissue‐specific differences in isoforms allow Na(+), K(+)‐ATPase function to be tightly regulated, as they control sensitivity to ions and inhibitors. Uterine contraction relies on the activity of the Na(+), K(+) ATPase, which creates ionic gradients that drive excitation‐contracti...

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Detalles Bibliográficos
Autores principales: Floyd, Rachel V., Mobasheri, Ali, Wray, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727280/
https://www.ncbi.nlm.nih.gov/pubmed/29208689
http://dx.doi.org/10.14814/phy2.13527