Mechanism of inhibition of taurolithocholate‐induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate

Taurolithocholate (TLC) produces cholestasis by inhibiting biliary solute secretion in part by retrieving MRP2 from the plasma membrane (PM). Tauroursodeoxycholate (TUDC) and cAMP reverse TLC‐induced cholestasis by inhibiting TLC‐induced retrieval of MRP2. However, cellular mechanisms for this rever...

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Detalles Bibliográficos
Autores principales: Park, Se Won, Webster, Cynthia R. L., Anwer, Mohammed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727282/
https://www.ncbi.nlm.nih.gov/pubmed/29192063
http://dx.doi.org/10.14814/phy2.13529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727282/
https://www.ncbi.nlm.nih.gov/pubmed/29192063
http://dx.doi.org/10.14814/phy2.13529

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