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Docosahexaenoic acid counteracts palmitate‐induced endoplasmic reticulum stress in C2C12 myotubes: Impact on muscle atrophy

Lipid accumulation in skeletal muscle results in dysregulation of protein metabolism and muscle atrophy. We previously reported that treating C2C12 myotubes with palmitate (PA), a saturated fatty acid, increases the overall rate of proteolysis via activation of the ubiquitin‐proteasome and autophagy...

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Detalles Bibliográficos
Autores principales: Woodworth‐Hobbs, Myra E., Perry, Ben D., Rahnert, Jill A., Hudson, Matthew B., Zheng, Bin, Russ Price, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727283/
https://www.ncbi.nlm.nih.gov/pubmed/29199180
http://dx.doi.org/10.14814/phy2.13530