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Dysregulation of junctional adhesion molecule‐A contributes to ethanol‐induced barrier disruption in intestinal epithelial cell monolayers

Alcohol consumption promotes loss of intestinal barrier function. However, mechanisms by which ethanol affects the tight junction (TJ), the cellular structure responsible for maintaining the gut epithelial barrier, are not well understood. Three classes of transmembrane proteins comprise TJs: occlud...

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Detalles Bibliográficos
Autores principales: Chopyk, Daniel M., Kumar, Pradeep, Raeman, Reben, Liu, Yunshan, Smith, Tekla, Anania, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727288/
https://www.ncbi.nlm.nih.gov/pubmed/29208693
http://dx.doi.org/10.14814/phy2.13541