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Comparison of the mRNA expression profile of B‐cell receptor components in normal CD5‐high B‐lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70

The B‐cell receptor (BCR) signaling pathway is of great importance for B‐cell survival and proliferation. The BCR expressed on malignant B‐CLL cells contributes to the disease pathogenesis, and its signaling pathway is currently the target of several therapeutic strategies. Although various BCR alte...

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Detalles Bibliográficos
Autores principales: Gladkikh, Aleena A., Potashnikova, Daria M., Tatarskiy, Victor, Yastrebova, Margarita, Khamidullina, Alvina, Barteneva, Natasha, Vorobjev, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727315/
https://www.ncbi.nlm.nih.gov/pubmed/29125235
http://dx.doi.org/10.1002/cam4.1257