Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation

We analyzed the tear film proteome of patients with dry eye (DE), meibomian gland dysfunction (MGD), and normal volunteers (CT). Tear samples were collected from 70 individuals. Of these, 37 samples were analyzed using spectral-counting-based LC-MS/MS label-free quantitation, and 33 samples were eva...

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Detalles Bibliográficos
Autores principales: Soria, Javier, Acera, Arantxa, Merayo-LLoves, Jesús, Durán, Juan A., González, Nerea, Rodriguez, Sandra, Bistolas, Nikitas, Schumacher, Soeren, Bier, Frank F., Peter, Harald, Stöcklein, Walter, Suárez, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727318/
https://www.ncbi.nlm.nih.gov/pubmed/29234088
http://dx.doi.org/10.1038/s41598-017-17536-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727318/
https://www.ncbi.nlm.nih.gov/pubmed/29234088
http://dx.doi.org/10.1038/s41598-017-17536-2

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