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Phosphorylated ERK is a potential prognostic biomarker for Sorafenib response in hepatocellular carcinoma

Sorafenib, the only approved drug for hepatocellular carcinoma, acts as a remarkable inhibitor of Raf serine‐threonine kinases. However, Sorafenib is expensive, and clinical experience shows that it is not an effective treatment for many patients. Previous study has demonstrated that phosphorylated...

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Detalles Bibliográficos
Autores principales: Liang, Yuelong, Chen, Jiang, Yu, Qingsong, Ji, Tong, Zhang, Bin, Xu, Junjie, Dai, Yi, Xie, Yangyang, Lin, Hui, Liang, Xiao, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727337/
https://www.ncbi.nlm.nih.gov/pubmed/29030911
http://dx.doi.org/10.1002/cam4.1228