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Molecular evolution of acetohydroxyacid synthase in bacteria

Acetohydroxyacid synthase (AHAS) is the key enzyme in the biosynthetic pathways of branched chain amino acids in bacteria. Since it does not exist in animal and plant cells, AHAS is an attractive target for developing antimicrobials and herbicides. In some bacteria, there is a single copy of AHAS, w...

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Detalles Bibliográficos
Autores principales: Liu, Yadi, Li, Yanyan, Wang, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727371/
https://www.ncbi.nlm.nih.gov/pubmed/28782269
http://dx.doi.org/10.1002/mbo3.524