CTCF driven TERRA transcription facilitates completion of telomere DNA replication

Telomere repeat DNA forms a nucleo-protein structure that can obstruct chromosomal DNA replication, especially under conditions of replication stress. Transcription of telomere repeats can initiate at subtelomeric CTCF-binding sites to generate telomere repeat-encoding RNA (TERRA), but the role of t...

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Detalles Bibliográficos
Autores principales: Beishline, Kate, Vladimirova, Olga, Tutton, Stephen, Wang, Zhuo, Deng, Zhong, Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727389/
https://www.ncbi.nlm.nih.gov/pubmed/29235471
http://dx.doi.org/10.1038/s41467-017-02212-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727389/
https://www.ncbi.nlm.nih.gov/pubmed/29235471
http://dx.doi.org/10.1038/s41467-017-02212-w

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