Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis

The crystal structure of the large terminase from the Geobacillus stearothermophilus bacteriophage D6E shows a unique relative orientation of the N-terminal adenosine triphosphatase (ATPase) and C-terminal nuclease domains. This monomeric ‘initiation’ state with the two domains ‘locked’ together is...

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Detalles Bibliográficos
Autores principales: Xu, Rui-Gang, Jenkins, Huw T., Antson, Alfred A., Greive, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727402/
https://www.ncbi.nlm.nih.gov/pubmed/29069443
http://dx.doi.org/10.1093/nar/gkx947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727402/
https://www.ncbi.nlm.nih.gov/pubmed/29069443
http://dx.doi.org/10.1093/nar/gkx947

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