Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein

CRISPR (clustered regularly interspaced short palindromic repeat)-Cas adaptive immune systems are prevalent defense mechanisms in bacteria and archaea. They provide sequence-specific detection and neutralization of foreign nucleic acids such as bacteriophages and plasmids. One mechanism by which pha...

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Detalles Bibliográficos
Autores principales: Pawluk, April, Shah, Megha, Mejdani, Marios, Calmettes, Charles, Moraes, Trevor F., Davidson, Alan R., Maxwell, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727412/
https://www.ncbi.nlm.nih.gov/pubmed/29233895
http://dx.doi.org/10.1128/mBio.01751-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727412/
https://www.ncbi.nlm.nih.gov/pubmed/29233895
http://dx.doi.org/10.1128/mBio.01751-17

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