Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types

We report a simple strategy for the creation of lentiviral vectors specific to any desired target cells. SpyTag is inserted into an engineered Sindbis virus envelope protein and displayed on the lentivirus surface to create Sindbis virus-SpyTag pseudoparticles (Sind-SpyTag-pp). The SpyTag serves as...

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Detalles Bibliográficos
Autores principales: Kasaraneni, Nagarjun, Chamoun-Emanuelli, Ana M., Wright, Gus, Chen, Zhilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727413/
https://www.ncbi.nlm.nih.gov/pubmed/29233896
http://dx.doi.org/10.1128/mBio.01860-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727413/
https://www.ncbi.nlm.nih.gov/pubmed/29233896
http://dx.doi.org/10.1128/mBio.01860-17

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