Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility

Dynamin-like guanylate binding proteins (GBPs) are gamma interferon (IFN-γ)-inducible host defense proteins that can associate with cytosol-invading bacterial pathogens. Mouse GBPs promote the lytic destruction of targeted bacteria in the host cell cytosol, but the antimicrobial function of human GB...

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Detalles Bibliográficos
Autores principales: Piro, Anthony S., Hernandez, Dulcemaria, Luoma, Sarah, Feeley, Eric M., Finethy, Ryan, Yirga, Azeb, Frickel, Eva M., Lesser, Cammie F., Coers, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727416/
https://www.ncbi.nlm.nih.gov/pubmed/29233899
http://dx.doi.org/10.1128/mBio.01979-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727416/
https://www.ncbi.nlm.nih.gov/pubmed/29233899
http://dx.doi.org/10.1128/mBio.01979-17

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