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Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development

Malaria parasites have a complex life cycle with multiple developmental stages in mosquito and vertebrate hosts, and different developmental stages express unique sets of genes. Unexpectedly, many transcription factors (TFs) commonly found in eukaryotic organisms are absent in malaria parasites; ins...

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Detalles Bibliográficos
Autores principales: Zhang, Cui, Li, Zhenkui, Cui, Huiting, Jiang, Yuanyuan, Yang, Zhenke, Wang, Xu, Gao, Han, Liu, Cong, Zhang, Shujia, Su, Xin-zhuan, Yuan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727417/
https://www.ncbi.nlm.nih.gov/pubmed/29233900
http://dx.doi.org/10.1128/mBio.01986-17