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SYK kinase mediates brown fat differentiation and activation

Brown adipose tissue (BAT) metabolism influences glucose homeostasis and metabolic health in mice and humans. Sympathetic stimulation of β-adrenergic receptors in response to cold induces proliferation, differentiation, and UCP1 expression in pre-adipocytes and mature brown adipocytes. Here we show...

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Detalles Bibliográficos
Autores principales: Knoll, Marko, Winther, Sally, Natarajan, Anirudh, Yang, Huan, Jiang, Mengxi, Thiru, Prathapan, Shahsafaei, Aliakbar, Chavarria, Tony E., Lamming, Dudley W., Sun, Lei, Hansen, Jacob B., Lodish, Harvey F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727434/
https://www.ncbi.nlm.nih.gov/pubmed/29235464
http://dx.doi.org/10.1038/s41467-017-02162-3