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SYK kinase mediates brown fat differentiation and activation
Brown adipose tissue (BAT) metabolism influences glucose homeostasis and metabolic health in mice and humans. Sympathetic stimulation of β-adrenergic receptors in response to cold induces proliferation, differentiation, and UCP1 expression in pre-adipocytes and mature brown adipocytes. Here we show...
Autores principales: | Knoll, Marko, Winther, Sally, Natarajan, Anirudh, Yang, Huan, Jiang, Mengxi, Thiru, Prathapan, Shahsafaei, Aliakbar, Chavarria, Tony E., Lamming, Dudley W., Sun, Lei, Hansen, Jacob B., Lodish, Harvey F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727434/ https://www.ncbi.nlm.nih.gov/pubmed/29235464 http://dx.doi.org/10.1038/s41467-017-02162-3 |
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