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Common TFIIH recruitment mechanism in global genome and transcription-coupled repair subpathways

Nucleotide excision repair is initiated by two different damage recognition subpathways, global genome repair (GGR) and transcription-coupled repair (TCR). In GGR, XPC detects DNA lesions and recruits TFIIH via interaction with the pleckstrin homology (PH) domain of TFIIH subunit p62. In TCR, an elo...

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Detalles Bibliográficos
Autores principales: Okuda, Masahiko, Nakazawa, Yuka, Guo, Chaowan, Ogi, Tomoo, Nishimura, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727438/
https://www.ncbi.nlm.nih.gov/pubmed/29069470
http://dx.doi.org/10.1093/nar/gkx970