Conformational profiling of a G-rich sequence within the c-KIT promoter

G-quadruplexes (G4) within oncogene promoters are considered to be promising anticancer targets. However, often they undergo complex structural rearrangements that preclude a precise description of the optimal target. Moreover, even when solved structures are available, they refer to the thermodynam...

Descripción completa

Detalles Bibliográficos
Autores principales: Rigo, Riccardo, Dean, William L., Gray, Robert D., Chaires, Jonathan B., Sissi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727440/
https://www.ncbi.nlm.nih.gov/pubmed/29069417
http://dx.doi.org/10.1093/nar/gkx983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727440/
https://www.ncbi.nlm.nih.gov/pubmed/29069417
http://dx.doi.org/10.1093/nar/gkx983

Ejemplares similares