Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity

Because of the requirement of oxygen (O(2)) to produce energy, aerobic organisms developed mechanisms to protect themselves against a shortage of oxygen in both acute status and chronic status. To date, how organisms tolerate acute hypoxia and the underlying mechanisms remain largely unknown. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Dawei, Du, Juan, Zhou, Chi, Li, Zhi, Liu, Xing, Ouyang, Gang, Xiao, Wuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727443/
https://www.ncbi.nlm.nih.gov/pubmed/29036334
http://dx.doi.org/10.1093/nar/gkx869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727443/
https://www.ncbi.nlm.nih.gov/pubmed/29036334
http://dx.doi.org/10.1093/nar/gkx869

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