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CsrA maximizes expression of the AcrAB multidrug resistance transporter

Carbon Storage Regulator A (CsrA) is an RNA binding protein that acts as a global regulator of diverse genes. Using a combination of genetics and biochemistry we show that CsrA binds directly to the 5′ end of the transcript encoding AcrAB. Deletion of csrA or mutagenesis of the CsrA binding sites re...

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Detalles Bibliográficos
Autores principales: Ricci, Vito, Attah, Victoria, Overton, Tim, Grainger, David C., Piddock, Laura J.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727465/
https://www.ncbi.nlm.nih.gov/pubmed/29040729
http://dx.doi.org/10.1093/nar/gkx929