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Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability

Clostridium difficile infection is a growing problem in healthcare settings worldwide and results in a considerable socioeconomic impact. New hypervirulent strains and acquisition of antibiotic resistance exacerbates pathogenesis; however, the survival strategy of C. difficile in the challenging gut...

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Detalles Bibliográficos
Autores principales: Jain, Shailesh, Smyth, Deborah, O’Hagan, Barry M. G., Heap, John T., McMullan, Geoff, Minton, Nigel P., Ternan, Nigel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727486/
https://www.ncbi.nlm.nih.gov/pubmed/29235503
http://dx.doi.org/10.1038/s41598-017-17583-9