Cargando…
Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability
Clostridium difficile infection is a growing problem in healthcare settings worldwide and results in a considerable socioeconomic impact. New hypervirulent strains and acquisition of antibiotic resistance exacerbates pathogenesis; however, the survival strategy of C. difficile in the challenging gut...
Autores principales: | Jain, Shailesh, Smyth, Deborah, O’Hagan, Barry M. G., Heap, John T., McMullan, Geoff, Minton, Nigel P., Ternan, Nigel G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727486/ https://www.ncbi.nlm.nih.gov/pubmed/29235503 http://dx.doi.org/10.1038/s41598-017-17583-9 |
Ejemplares similares
-
Comparative Transcriptional Analysis of Clinically Relevant Heat Stress Response in Clostridium difficile Strain 630
por: Ternan, Nigel G., et al.
Publicado: (2012) -
Semiquantitative Analysis of Clinical Heat Stress in Clostridium difficile Strain 630 Using a GeLC/MS Workflow with emPAI Quantitation
por: Ternan, Nigel G., et al.
Publicado: (2014) -
TcdC Does Not Significantly Repress Toxin Expression in Clostridium difficile 630ΔErm
por: Bakker, Dennis, et al.
Publicado: (2012) -
Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity
por: Ternan, Nigel George, et al.
Publicado: (2018) -
Time-resolved amino acid uptake of Clostridium difficile 630Δerm and concomitant fermentation product and toxin formation
por: Neumann-Schaal, Meina, et al.
Publicado: (2015)