Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium

Fibromyalgia (FM) results in pain characterized by low selenium (Se) levels, excessive Ca(2+) influx, reactive oxygen species (ROS) production, and acidic pH. TRPM2 and TRPV1 are activated by ROS and acid; nevertheless, their roles have not been elucidated in FM. Therefore, we investigated the contr...

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Detalles Bibliográficos
Autores principales: Yüksel, Esra, Nazıroğlu, Mustafa, Şahin, Mehmet, Çiğ, Bilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727501/
https://www.ncbi.nlm.nih.gov/pubmed/29235496
http://dx.doi.org/10.1038/s41598-017-17715-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727501/
https://www.ncbi.nlm.nih.gov/pubmed/29235496
http://dx.doi.org/10.1038/s41598-017-17715-1

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