Pharmacological modulation of Kv3.1 mitigates auditory midbrain temporal processing deficits following auditory nerve damage

Higher stages of central auditory processing compensate for a loss of cochlear nerve synapses by increasing the gain on remaining afferent inputs, thereby restoring firing rate codes for rudimentary sound features. The benefits of this compensatory plasticity are limited, as the recovery of precise...

Descripción completa

Detalles Bibliográficos
Autores principales: Chambers, Anna R., Pilati, Nadia, Balaram, Pooja, Large, Charles H., Kaczmarek, Leonard K., Polley, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727503/
https://www.ncbi.nlm.nih.gov/pubmed/29235497
http://dx.doi.org/10.1038/s41598-017-17406-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727503/
https://www.ncbi.nlm.nih.gov/pubmed/29235497
http://dx.doi.org/10.1038/s41598-017-17406-x

Ejemplares similares