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Computational exploration of the chemical structure space of possible reverse tricarboxylic acid cycle constituents

The reverse tricarboxylic acid (rTCA) cycle has been explored from various standpoints as an idealized primordial metabolic cycle. Its simplicity and apparent ubiquity in diverse organisms across the tree of life have been used to argue for its antiquity and its optimality. In 2000 it was proposed t...

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Detalles Bibliográficos
Autores principales: Meringer, Markus, Cleaves, H. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727506/
https://www.ncbi.nlm.nih.gov/pubmed/29235498
http://dx.doi.org/10.1038/s41598-017-17345-7