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Ubiquitin-conjugating enzyme E2T (UBE2T) and denticleless protein homolog (DTL) are linked to poor outcome in breast and lung cancers

Protein ubiquitination and degradation represent druggable vulnerabilities of cancer cells. We used gene expression and functional annotation analyses to identify genes in the ubiquitin pathway which are differentially expressed between normal breast and basal-like tumors. With this approach we iden...

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Detalles Bibliográficos
Autores principales: Perez-Peña, Javier, Corrales-Sánchez, Verónica, Amir, Eitan, Pandiella, Atanasio, Ocana, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727519/
https://www.ncbi.nlm.nih.gov/pubmed/29235520
http://dx.doi.org/10.1038/s41598-017-17836-7