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Identification of nonsense-mediated mRNA decay pathway as a critical regulator of p53 isoform β
Human TP53 gene encodes the tumor suppressor p53 and, via alternative splicing, the p53β and γ isoforms. Numerous studies have shown that p53β/γ can modulate p53 functions and are critically involved in regulation of cellular response to stress conditions. However, it is not fully understood how the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727530/ https://www.ncbi.nlm.nih.gov/pubmed/29235495 http://dx.doi.org/10.1038/s41598-017-17283-4 |