Cargando…

Hypoxia-inducible factor 1 mediates intermittent hypoxia-induced migration of human breast cancer MDA-MB-231 cells

Metastasis is the major cause of triple-negative breast cancer (TNBC)-associated mortality. Hypoxia promotes cancer cell migration and remote metastasis, which occur with hypoxia inducible factor 1α (HIF-1α) stabilization and vimentin upregulation. However, the evolutionary dynamics that link the ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Litao, Liu, Wenlan, Wang, Lili, Zhu, Ting, Zhong, Jianhua, Xie, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727604/
https://www.ncbi.nlm.nih.gov/pubmed/29250173
http://dx.doi.org/10.3892/ol.2017.7223