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Dynamics of Neutrophils-to-Lymphocyte Ratio Predict Outcomes of PD-1/PD-L1 Blockade

INTRODUCTION: Baseline neutrophil-to-lymphocyte ratio (NLR) has been repeatedly reported as a significant prognostic factor in advanced cancer patients. We explored whether changes in NLR may predict outcome of advanced cancer patients enrolled into phase 1 trials and treated with PD-1/PD-L1 inhibit...

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Detalles Bibliográficos
Autores principales: Moschetta, Michele, Uccello, Mario, Kasenda, Benjamin, Mak, Gabriel, McClelland, Anissa, Boussios, Stergios, Forster, Martin, Arkenau, Hendrik-Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727693/
https://www.ncbi.nlm.nih.gov/pubmed/29318140
http://dx.doi.org/10.1155/2017/1506824