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Gene Expression Changes in Long-Term In Vitro Human Blood-Brain Barrier Models and Their Dependence on a Transwell Scaffold Material

Disruption of the blood-brain barrier (BBB) is the hallmark of many neurovascular disorders, making it a critically important focus for therapeutic options. However, testing the effects of either drugs or pathological agents is difficult due to the potentially damaging consequences of altering the n...

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Detalles Bibliográficos
Autores principales: Gaston, Joel D., Bischel, Lauren L., Fitzgerald, Lisa A., Cusick, Kathleen D., Ringeisen, Bradley R., Pirlo, Russell K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727720/
https://www.ncbi.nlm.nih.gov/pubmed/29317995
http://dx.doi.org/10.1155/2017/5740975