Cargando…

Gene Expression Changes in Long-Term In Vitro Human Blood-Brain Barrier Models and Their Dependence on a Transwell Scaffold Material

Disruption of the blood-brain barrier (BBB) is the hallmark of many neurovascular disorders, making it a critically important focus for therapeutic options. However, testing the effects of either drugs or pathological agents is difficult due to the potentially damaging consequences of altering the n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gaston, Joel D., Bischel, Lauren L., Fitzgerald, Lisa A., Cusick, Kathleen D., Ringeisen, Bradley R., Pirlo, Russell K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727720/ https://www.ncbi.nlm.nih.gov/pubmed/29317995 http://dx.doi.org/10.1155/2017/5740975

Ejemplares similares

Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices
por: Frost, Timothy S., et al.
Publicado: (2019)

Selection and Evaluation of Reference Genes for Expression Studies with Quantitative PCR in the Model Fungus Neurospora crassa under Different Environmental Conditions in Continuous Culture
por: Cusick, Kathleen D., et al.
Publicado: (2014)

A Novel Transwell Blood Brain Barrier Model Using Primary Human Cells
por: Stone, Nicole L., et al.
Publicado: (2019)

Quantitative Analysis of a Pilot Transwell Barrier Model with Automated Sampling and Mathematical Modeling
por: Tárnoki-Zách, Júlia, et al.
Publicado: (2023)

An Improved Transwell Design for Microelectrode Ion-Flux Measurements
por: Buchroithner, Boris, et al.
Publicado: (2021)

Open source board based acoustofluidic transwells for reversible disruption of the blood–brain barrier for therapeutic delivery
por: Wang, Ke, et al.
Publicado: (2023)

Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model
por: Merolle, Matilde, et al.
Publicado: (2020)

Comparative Analysis of Inflammatory Cytokine Release and Alveolar Epithelial Barrier Invasion in a Transwell(®) Bilayer Model of Mucormycosis
por: Belic, Stanislav, et al.
Publicado: (2019)

3D-Printed electrochemical sensor-integrated transwell systems
por: Ramiah Rajasekaran, Pradeep, et al.
Publicado: (2020)

Transwell migration assay to interrogate human CAR-T cell chemotaxis
por: Oner, Arman, et al.
Publicado: (2022)

Transwell-Hypoxia Method Facilitates the Outgrowth of 3D-Printed Collagen Scaffolds Loaded with Cryopreserved Patient-Derived Melanoma Explants
por: Park, MinJi, et al.
Publicado: (2022)

Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations
por: Chang, Shu-Han, et al.
Publicado: (2021)

Optimization of the Transwell(®) System for Assessing the Dissolution Behavior of Orally Inhaled Drug Products through In Vitro and In Silico Approaches
por: Amini, Elham, et al.
Publicado: (2021)

Tissue-on-a-Chip: Microphysiometry With Human 3D Models on Transwell Inserts
por: Schmidt, Christian, et al.
Publicado: (2020)

A Transwell-Based Vascularized Model to Investigate the Effect of Interstitial Flow on Vasculogenesis
por: Deng, Pengwei, et al.
Publicado: (2022)

Development and validation of an open-source, disposable, 3D-printed in vitro environmental exposure system for Transwell culture inserts
por: Chandiramohan, Abiram, et al.
Publicado: (2021)

Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model
por: Song, Ren, et al.
Publicado: (2022)

A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication
por: Thayanithy, Venugopal, et al.
Publicado: (2017)

Fibroblast-like cells change gene expression of bone remodelling markers in transwell cultures
por: Hartmann, Eliza S., et al.
Publicado: (2020)

TEER and Ion Selective Transwell-Integrated Sensors System for Caco-2 Cell Model
por: Sciurti, Elisa, et al.
Publicado: (2023)

Suppressing the Neurospora crassa circadian clock while maintaining light responsiveness in continuous stirred tank reactors
por: Cockrell, Allison L., et al.
Publicado: (2015)

Isolation, culture, and cryosectioning of primary porcine retinal pigment epithelium on transwell cell culture inserts
por: Hood, Erika M.S., et al.
Publicado: (2022)

The Effect of Platelet Rich Plasma on Chondrogenic Differentiation of Human Adipose Derived Stem Cells in Transwell Culture
por: Mardani, Mohammad, et al.
Publicado: (2013)

Development of a miniaturized 96-Transwell air–liquid interface human small airway epithelial model
por: Bluhmki, Teresa, et al.
Publicado: (2020)

Protocol to quantify enzymatic effects on vitreous liquefaction in porcine eyes using a transwell-plate system
por: Wolf, Julian, et al.
Publicado: (2022)

Comparison of LPS-stimulated release of cytokines in punch versus transwell tissue culture systems of human gestational membranes
por: Miller, Mark F, et al.
Publicado: (2010)

I-AbACUS: a Reliable Software Tool for the Semi-Automatic Analysis of Invasion and Migration Transwell Assays
por: Cortesi, Marilisa, et al.
Publicado: (2018)

Role of peptide transporters in small peptide uptake of bovine mammary epithelial cells cultured in a transwell chamber
por: Zhou, Miaomiao, et al.
Publicado: (2023)

Usefulness of a humanized tricellular static transwell blood–brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system
por: Nakayama-Kitamura, Kimiko, et al.
Publicado: (2023)

Selection and Evaluation of Reference Genes for Reverse Transcription-Quantitative PCR Expression Studies in a Thermophilic Bacterium Grown under Different Culture Conditions
por: Cusick, Kathleen D., et al.
Publicado: (2015)

An Open-Source Add-On EVOM(®) Device for Real-Time Transepithelial/Endothelial Electrical Resistance Measurements in Multiple Transwell Samples
por: Raut, Bibek, et al.
Publicado: (2021)

Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study
por: Zhang, Xiao-Yan, et al.
Publicado: (2021)

Study of the ichthyotoxic microalga Heterosigma akashiwo by transcriptional activation of sublethal marker Hsp70b in Transwell co-culture assays
por: Astuya, Allisson, et al.
Publicado: (2018)

Establishment of a 96-well transwell system using primary human gut organoids to capture multiple quantitative pathway readouts
por: Wright, Charles W., et al.
Publicado: (2023)

Matrix Metalloproteinase Response of Dendritic Cell, Gingival Epithelial Keratinocyte, and T-Cell Transwell Co-Cultures Treated with Porphyromonas gingivalis Hemagglutinin-B
por: Bates, Amber M., et al.
Publicado: (2018)

Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model
por: Bluhmki, Teresa, et al.
Publicado: (2021)

Germans’ awareness of refugees’ information barriers regarding health care access: a cross-sectional study
por: Schubert, Saskia, et al.
Publicado: (2023)

Induction of Human Umbilical Mesenchymal Stem Cell Differentiation Into Retinal Pigment Epithelial Cells Using a Transwell-Based Co-culture System
por: Chang, Yu-Hsun, et al.
Publicado: (2022)

Fading distributed scaffolds: the importance of complementarity between teacher and material scaffolds
por: Martin, Nicole D., et al.
Publicado: (2018)

In-Vitro and In-Silico Assessment of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Film-Forming Foam (AFFF) Binding to Human Serum Albumin
por: Li, Wenting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dmn3q7jpds4odmiffo42qa1c32