Histone Deacetylase (HDAC) Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA), Induces Apoptosis in Prostate Cancer Cell Lines via the Akt/FOXO3a Signaling Pathway

BACKGROUND: Histone deacetylase (HDAC) inhibitors are emerging as a new class of anti-cancer drugs that promote cancer cell apoptosis, and include suberoylanilide hydroxamic acid (SAHA). The aim of this study was to investigate the mechanism of SAHA-induced apoptosis in human prostate cancer cell li...

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Detalles Bibliográficos
Autores principales: Shi, Xuan-Yan, Ding, Wei, Li, Tie-Qiu, Zhang, Yi-Xiong, Zhao, Shan-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727751/
https://www.ncbi.nlm.nih.gov/pubmed/29211704
http://dx.doi.org/10.12659/MSM.904597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727751/
https://www.ncbi.nlm.nih.gov/pubmed/29211704
http://dx.doi.org/10.12659/MSM.904597

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