The eIF4E2-Directed Hypoxic Cap-Dependent Translation Machinery Reveals Novel Therapeutic Potential for Cancer Treatment

Hypoxia is an aspect of the tumor microenvironment that is linked to radiation and chemotherapy resistance, metastasis, and poor prognosis. The ability of hypoxic tumor cells to achieve these cancer hallmarks is, in part, due to changes in their gene expression profiles. Cancer cells have a high dem...

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Detalles Bibliográficos
Autores principales: Melanson, Gaelan, Timpano, Sara, Uniacke, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727761/
https://www.ncbi.nlm.nih.gov/pubmed/29317983
http://dx.doi.org/10.1155/2017/6098107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727761/
https://www.ncbi.nlm.nih.gov/pubmed/29317983
http://dx.doi.org/10.1155/2017/6098107

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