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Benznidazole affects expression of Th1, Th17 and Treg cytokines during acute experimental Trypanosoma cruzi infection

BACKGROUND: The present study evaluated the effect of treatment with benznidazole on mRNA expression of IFN-γ, IL-17, IL-10, TGF-β and FoxP3 in spleen and heart tissue of BALB/c mice in the acute phase of an experimental infection with Trypanosoma cruzi, strains JLP or Y. METHODS: The mRNA expressio...

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Detalles Bibliográficos
Autores principales: Gatto, Mariana, Oliveira, Larissa Ragozo Cardoso, De Nuzzi Dias, Fernanda, Araújo Júnior, João Pessoa, Lima, Carlos Roberto Gonçalves, Lordelo, Eliana Peresi, dos Santos, Rodrigo Mattos, Kurokawa, Cilmery Suemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727918/
https://www.ncbi.nlm.nih.gov/pubmed/29255475
http://dx.doi.org/10.1186/s40409-017-0137-4