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Favourable metabolic profile sustains mitophagy and prevents metabolic abnormalities in metabolically healthy obese individuals
BACKGROUND: Obesity-mediated oxidative stress results in mitochondrial dysfunction, which has been implicated in the pathogenesis of metabolic syndrome and T2DM. Recently, mitophagy, a cell-reparative process has emerged as a key facet in maintaining the mitochondrial health, which may contribute to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728047/ https://www.ncbi.nlm.nih.gov/pubmed/29255491 http://dx.doi.org/10.1186/s13098-017-0298-x |