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Simvastatin intolerance genetic determinants: some features in ethnic Uzbek patients with coronary artery disease

INTRODUCTION: The objective is to study the influence of CYP3A5 (6986A>G), CYP2C9 (430C>T), CYP2C9 (1075A>C), SLCO1B1 (521T>C) and BCRP (ABCG2, 421C>A) gene polymorphisms on the development of simvastatin intolerance in ethnic Uzbek patients with coronary artery disease (CAD). MATERIA...

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Detalles Bibliográficos
Autores principales: Shek, Aleksandr B., Kurbanov, Ravshanbek D., Abdullaeva, Guzal J., Nagay, Aleksandr V., Hoshimov, Shavkat U., Nizamov, Ulugbek I., Ziyaeva, Adolat V., Alieva, Rano B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728073/
https://www.ncbi.nlm.nih.gov/pubmed/29242847
http://dx.doi.org/10.5114/amsad.2017.70597