Structure modeling of RNA using sparse NMR constraints

RNAs fold into distinct molecular conformations that are often essential for their functions. Accurate structure modeling of complex RNA motifs, including ubiquitous non-canonical base pairs and pseudoknots, remains a challenge. Here, we present an NMR-guided all-atom discrete molecular dynamics (DM...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Benfeard, Zhao, Bo, Tandon, Arpit, Ding, Feng, Weeks, Kevin M., Zhang, Qi, Dokholyan, Nikolay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728392/
https://www.ncbi.nlm.nih.gov/pubmed/29165648
http://dx.doi.org/10.1093/nar/gkx1058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728392/
https://www.ncbi.nlm.nih.gov/pubmed/29165648
http://dx.doi.org/10.1093/nar/gkx1058

Ejemplares similares