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Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C

Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells. This hampers the investigation of chromatin architecture in rare cell populations. We present a new low-input Capt...

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Detalles Bibliográficos
Autores principales: Oudelaar, A. Marieke, Davies, James O.J., Downes, Damien J., Higgs, Douglas R., Hughes, Jim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728395/
https://www.ncbi.nlm.nih.gov/pubmed/29186505
http://dx.doi.org/10.1093/nar/gkx1194