Expanding the repertoire of DNA shape features for genome-scale studies of transcription factor binding

Uncovering the mechanisms that affect the binding specificity of transcription factors (TFs) is critical for understanding the principles of gene regulation. Although sequence-based models have been used successfully to predict TF binding specificities, we found that including DNA shape information...

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Detalles Bibliográficos
Autores principales: Li, Jinsen, Sagendorf, Jared M., Chiu, Tsu-Pei, Pasi, Marco, Perez, Alberto, Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728407/
https://www.ncbi.nlm.nih.gov/pubmed/29165643
http://dx.doi.org/10.1093/nar/gkx1145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728407/
https://www.ncbi.nlm.nih.gov/pubmed/29165643
http://dx.doi.org/10.1093/nar/gkx1145

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