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EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice

EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy cardiomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection of chimeric ephrinA1-Fc at the time of ischemia reduced injury in the nonrepe...

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Detalles Bibliográficos
Autores principales: DuSablon, Augustin, Parks, Justin, Whitehurst, K’Shylah, Estes, Heather, Chase, Robert, Vlahos, Eleftherios, Sharma, Uma, Wert, David, Virag, Jitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728502/
https://www.ncbi.nlm.nih.gov/pubmed/29236774
http://dx.doi.org/10.1371/journal.pone.0189307