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Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations

While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood. Here we investigated thermally-activated spontaneous nucleosome sliding mechanisms developing and applying a co...

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Detalles Bibliográficos
Autores principales: Niina, Toru, Brandani, Giovanni B., Tan, Cheng, Takada, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728581/
https://www.ncbi.nlm.nih.gov/pubmed/29194442
http://dx.doi.org/10.1371/journal.pcbi.1005880