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Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations
While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood. Here we investigated thermally-activated spontaneous nucleosome sliding mechanisms developing and applying a co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728581/ https://www.ncbi.nlm.nih.gov/pubmed/29194442 http://dx.doi.org/10.1371/journal.pcbi.1005880 |