Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS

We utilized evidence for enhancer-promoter interactions from functional genomics data in order to build biological filters to narrow down the search space for two-way Single Nucleotide Polymorphism (SNP) interactions in Type 2 Diabetes (T2D) Genome Wide Association Studies (GWAS). This has led us to...

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Detalles Bibliográficos
Autores principales: Manduchi, Elisabetta, Chesi, Alessandra, Hall, Molly A., Grant, Struan F.A., Moore, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728670/
https://www.ncbi.nlm.nih.gov/pubmed/29218913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728670/
https://www.ncbi.nlm.nih.gov/pubmed/29218913

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