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Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release

Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1). cla-1 mutants exhibit defects in synaptic vesicle clustering, active zone structure and syn...

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Detalles Bibliográficos
Autores principales: Xuan, Zhao, Manning, Laura, Nelson, Jessica, Richmond, Janet E, Colón-Ramos, Daniel A, Shen, Kang, Kurshan, Peri T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728718/
https://www.ncbi.nlm.nih.gov/pubmed/29160205
http://dx.doi.org/10.7554/eLife.29276