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Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release
Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1). cla-1 mutants exhibit defects in synaptic vesicle clustering, active zone structure and syn...
Autores principales: | Xuan, Zhao, Manning, Laura, Nelson, Jessica, Richmond, Janet E, Colón-Ramos, Daniel A, Shen, Kang, Kurshan, Peri T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728718/ https://www.ncbi.nlm.nih.gov/pubmed/29160205 http://dx.doi.org/10.7554/eLife.29276 |
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