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Glutathione Enhances Antibiotic Efficiency and Effectiveness of DNase I in Disrupting Pseudomonas aeruginosa Biofilms While Also Inhibiting Pyocyanin Activity, Thus Facilitating Restoration of Cell Enzymatic Activity, Confluence and Viability

Pyocyanin secreted by Pseudomonas aeruginosa is a virulence factor that damages epithelial cells during infection through the action of reactive oxygen species, however, little is known about its direct effect on biofilms. We demonstrated that pyocyanin-producing P. aeruginosa strains (PA14WT, DKN37...

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Detalles Bibliográficos
Autores principales: Das, Theerthankar, Simone, Martin, Ibugo, Amaye I., Witting, Paul K., Manefield, Mike, Manos, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729223/
https://www.ncbi.nlm.nih.gov/pubmed/29312161
http://dx.doi.org/10.3389/fmicb.2017.02429