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Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats

BACKGROUND: Leucine-rich glioma-inactivated (LGI) proteins play a critical role in synaptic transmission. Dysfunction of these genes and encoded proteins is associated with neurological disorders such as genetic epilepsy or autoimmune limbic encephalitis in animals and human. Familial spontaneous ep...

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Detalles Bibliográficos
Autores principales: Yu, Yoshihiko, Hasegawa, Daisuke, Fujiwara-Igarashi, Aki, Hamamoto, Yuji, Mizoguchi, Shunta, Kuwabara, Takayuki, Fujita, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729232/
https://www.ncbi.nlm.nih.gov/pubmed/29237452
http://dx.doi.org/10.1186/s12917-017-1308-9