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Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites

BACKGROUND: Intracisternal A particle (IAP) is one of the most transpositionally active retrotransposons in the mouse genome, but its expression varies between cell types. This variation is believed to arise from differences in the epigenetic state (e.g., DNA methylation) of the 5′ long terminal rep...

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Detalles Bibliográficos
Autores principales: Shimosuga, Ken-ichi, Fukuda, Kei, Sasaki, Hiroyuki, Ichiyanagi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729234/
https://www.ncbi.nlm.nih.gov/pubmed/29255492
http://dx.doi.org/10.1186/s13100-017-0105-0