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Isogenic mice exhibit sexually-dimorphic DNA methylation patterns across multiple tissues

BACKGROUND: Cytosine methylation is a stable epigenetic modification of DNA that plays an important role in both normal physiology and disease. Most diseases exhibit some degree of sexual dimorphism, but the extent to which epigenetic states are influenced by sex is understudied and poorly understoo...

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Detalles Bibliográficos
Autores principales: McCormick, Helen, Young, Paul E., Hur, Suzy S. J., Booher, Keith, Chung, Hunter, Cropley, Jennifer E., Giannoulatou, Eleni, Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729250/
https://www.ncbi.nlm.nih.gov/pubmed/29237414
http://dx.doi.org/10.1186/s12864-017-4350-x